It follows their narrow 20 -24 defeat by the Leicester Tigers last Saturday.
Phil Dollman and Jack Nowell both return for the first time this season, taking over from Ceri Sweeney and Jack Arnott.
Two changes have been made to the starting line-up with Ben Moon coming in for Carl Rimmer, while Damian Welch comes in instead of Ryan Caldwell.
Plymouth Sessions won't go ahead next year
Promoter is axing some cities
Devon man jailed after Bristol rape
He met the victim on a dating app
Newton Abbot leisure centre could be relocated to make way for housing.
Body found in Bideford fire investigation
Three teenagers currently on bail
Royal Clarence Hotel redevelopment to start
Work to start on historic city centre building
Road closures for Tar Barrels event
Organisers list road closures and residents-only access.
