It follows their narrow 20 -24 defeat by the Leicester Tigers last Saturday.
Phil Dollman and Jack Nowell both return for the first time this season, taking over from Ceri Sweeney and Jack Arnott.
Two changes have been made to the starting line-up with Ben Moon coming in for Carl Rimmer, while Damian Welch comes in instead of Ryan Caldwell.
Car park flats could ruin Roman ruins
Roadworks frustrating Kingsbridge locals
Fears homes will create more gridlock on “car park” roads
Kart track wants to host large event
Devon rapist jailed for 26 years
125 homes proposed for Plympton
