The Exeter Chiefs take on Gloucester later in a match that could secure their place in the Heineken Cup.
Gloucester have already qualified for the Heineken Cup, but both clubs want to end the season with a flourish.
It'll be a memorable match for another reason as well - it's the last game being played by skipper Richard Baxter who's retiring from rugby.
Several other players are leaving as the season ends, and fans will be able to say goodbye to them as well after the match.
The Chiefs are expecting a huge crowd as tickets sold out two weeks ago.